dr. V. Giagka

Assistant Professor
Bioelectronics (BE), Department of Microelectronics

Expertise: Design and fabrication of active implantable devices; Analog and mixed-signal integrated circuits for biomedical applications

Themes: Electroceuticals, Flexible implants, Microsystem integration, Neuroprosthetics, - stimulation and -modulation

Biography

Vasiliki (Vasso) Giagka was born in Athens, Greece, in 1984. She received the M.Eng. degree in electronic and computer engineering from Aristotle University of Thessaloniki, Thessaloniki, Greece, in 2009. She then moved to London to join the Analogue and Biomedical Electronics Group at University College London, UK from where she received the PhD degree in 2014. In 2015 she joined the Implanted Devices Group at University College London, UK, as a research associate.

She currently, since September 2015, holds an assistant professor position at the Bioelectronics Group at Delft University of Technology, Delft, The Netherlands, and since September 2018 she is also leading the group Technologies for Bioelectronics, at Fraunhofer Institute for Reliability and Microintegration IZM, Berlin, Germany. Between her two affiliations, she is carrying out research on the design and fabrication of active neural interfaces. In particular, she is investigating new approaches for neural stimulation and wireless power transfer, as well as, implant miniaturization, microsystem integration, packaging and encapsulation to meet the challenges of bioelectronic medicines.

EE4555 Active implantable biomedical microsystems

ET4127 Themes in Biomedical Electronics

BioMEMS, biosensors, bioelectronics, ultrasound, microfluidics, wavefield imaging in monitoring, diagnosis and treatment

ET4130 Bioelectricity

Bioelectric phenomena, their sources and their mathematical analysis. Applications to neurostimulation and neuroprosthetic.

G3-M10 Minor Translational Neuroscience

The minor Translational Neuroscience for medical students covers the most important clinical (TRF) and research themes and gives the students a good insight in the added value of translational neuroscience research.

TM12003 Electrostimulation of Neurophysiological systems

POSITION-II: innovation in smart medical instruments

InForMed

An Integrated Pilot Line for Micro-Fabricated Medical Devices

  1. Comments on “Compact, Energy-Efficient High-Frequency Switched Capacitor Neural Stimulator With Active Charge Balancing"
    Alessandro Urso; Vasiliki Giagka; Wouter A. Serdijn;
    IEEE Transactions on Biomedical Circuits and Systems,
    2019. DOI: 10.1109/TBCAS.2019.2898555
    document

  2. An Ultra High-Frequency 8-Channel Neurostimulator Circuit with 68% Peak Power Efficiency
    Alessandro Urso; Vasiliki Giagka; Marijn Van Dongen; Wouter A. Serdijn;
    IEEE Transactions on Biomedical Circuits and Systems,
    2019. DOI: 10.1109/TBCAS.2019.2920294
    document

  3. EMBEDDING SMALL ELECTRONIC COMPONENTS INTO TINY FLEXIBLE IMPLANTS
    Anna Pak; Wouter A. Serdijn; Vasiliki Giagka;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  4. TOWARDS AN ACTIVE GRAPHENE-PDMS IMPLANT
    Gandhika K Wardhana; Wouter A. Serdijn; Sten Vollebregt; Vasiliki Giagka;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  5. POLYMER-ENCAPSULATED SINGLE-CHIP IMPLANTS FOR BIOELECTRONIC MEDICINE
    Kambiz Nanbakhsh; Wouter Serdijn; Vasiliki Giagka;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  6. TOWARDS A SEMI-FLEXIBLE PARYLENE-BASED PLATFORM TECHNOLOGY FOR ACTIVE IMPLANTABLE MEDICAL DEVICES
    Nasim Bakhshaee Babaroud; Marta Kluba; Ronald Dekker; Wouter Serdijn; Vasiliki Giagka;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  7. DESIGN AND CUSTOM FABRICATION OF A SMART TEMPERATURE SENSOR FOR AN ORGAN-ON-A-CHIP PLATFORM
    Martins da Ponte, Ronaldo; Vasiliki Giagka; Wouter A. Serdijn;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  8. DESIGN OF A MULTI-FUNCTIONAL SMART OPTRODE FOR ELECTROPHYSIOLOGY AND OPTOGENETICS
    Martins da Ponte, Ronaldo; Chengyu Huang; Vasiliki Giagka; Wouter A. Serdijn;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  9. THE INFLUENCE OF SOFT ENCAPSULATION MATERIALS ON THE WIRELESS POWER TRANSFER LINKS EFFICIENCY
    Anastasios Malissovas; Wouter A. Serdijn; Vasiliki Giagka;
    In Proc. 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  10. Pressure measurement of geometrically curved ultrasound transducer array for spatially specific stimulation of the vagus nerve
    S. Kawasaki; V. Giagka; M. de Haas; M. Louwerse; V. Henneken; C. van Heesch; R. Dekker;
    In Proc. IEEE Conf. on Neural Eng. (NER) 2019,
    San Francisco, CA, USA, March 2019.
    Abstract: ...
    Vagus nerve stimulators currently on the market can treat epilepsy and depression. Recent clinical trials show the potential for vagus nerve stimulation (VNS) to treat epilepsy, autoimmune disease, and traumatic brain injury. As we explore the benefits of VNS, it is expected that more possibilities for a new treatment will emerge in the future. However, existing VNS relies on electrical stimulation, whose limited selectivity (due to its poor spatial resolution) does not allow for any control over which therapeutic effect to induce. We hypothesize that by localizing the stimulation to fascicular level within the vagus nerve with focused ultrasound (US), it is possible to induce selective therapeutic effects with less side effects. A geometrically curve US transducer array that is small enough to wrap around the vagus nerve was fabricated. An experiment was conducted in water, with 48 US elements curved in a 1 mm radius and excited at 15 MHz to test the focusing capabilities of the device. The results show that the geometrical curvature focused the US to an area with a width and height of 110 μm and 550 μm. This will be equivalent to only 2.1% of the cross section of the vagus nerve, showing the potential of focused US to stimulate individual neuronal fibers within the vagus nerve selectively.

    document

  11. Embedding Small Electronic Components into Tiny Flexible Implants
    Anna Pak; Wouter A. Serdijn; Vasiliki Giagka;
    In Book of Abstracts, 2019 International Winterschool on Bioelectronics Conference (BioEl 2019),
    Kirchberg, Tirol, Austria, 16-23 March 2019.
    document

  12. Towards a Semi-Flexible Parylene-Based Platform Technology for Active Implantable Medical Devices
    Nasim Bakhshaee Babaroud; Marta Kluba; Ronald Dekker; Wouter Serdijn; Vasiliki Giagka;
    In Book of Abstracts, 2019 International Winterschool on Bioelectronics Conference (BioEl 2019),
    Kirchberg, Tirol, Austria, 16-23 March 2019.
    document

  13. Realizing flexible bioelectronic medicines for accessing the peripheral nerves – technology considerations
    Vasiliki Giagka; Wouter Serdijn;
    Bioelectronic Medicine,
    Volume 4, Issue 8, June 26 2018. DOI: 10.1186/s42234-018-0010-y
    document

  14. An Energy-Efficient, Inexpensive, Spinal Cord Stimulator with Adaptive Voltage Compliance for Freely Moving Rats
    Olafsdottir, Gudrun Erla; Serdijn, Wouter A.; Giagka, Vasiliki;
    In Proc. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society,
    Honolulu, HI, USA, IEEE, July 17-21 2018.
    document

  15. An Ultrasonically Powered and Controlled Ultra-High-Frequency Biphasic Electrical Neurostimulator
    Lucia Tacchetti; Wouter A. Serdijn; Vasiliki Giagka;
    In proc. IEEE Biomedical Circuits and Systems Conference (BioCAS 2018),
    IEEE, Oct. 17-19 2018.
    document

  16. Design and Custom Fabrication of a Smart Temperature Sensor for an Organ-on-a-chip Platform
    Martins da Ponte, Ronaldo; Vasiliki Giagka; Wouter A. Serdijn;
    In proc. IEEE Biomedical Circuits and Systems Conference (BioCAS 2018),
    IEEE, Oct. 17-19 2018.
    document

  17. MEMS-Electronics Integration: A Smart Temperature Sensor for an Organ-on-a-chip Platform
    Martins da Ponte, Ronaldo; Vasiliki Giagka; Wouter A. Serdijn;
    In Proc. ProRISC,
    Enschede, the Netherlands, June 7-8 2018.
    document

  18. Circuit and systems for polymeric implants: designing towards increased device lifetimes
    K. Nanbakhsh; V. Giagka; W.A. Serdijn;
    In Proc. ProRISC,
    Enschede, the Netherlands, June 7-8 2018.
    document

  19. Towards a Family of Customisable Flexible Neural Implants
    Vasiliki Giagka; Wouter Serdijn;
    In Book of Abstracts, 6th Dutch Bio-Medical Engineering Conference, 26 and 27 January 2017, Egmond aan Zee, The Netherlands,
    2017.
    document

  20. A wireless sensor for monitoring encapsulation performance in non-hermetic implants
    K. Nanbakhsh; V. Giagka; W. A. Serdijn;
    In Proc. Design of Medical Devices Conf. (DMD) 2017 Microfabrication for Medical Devices,
    Eindhoven, 14 – 15 Nov. 2017.
    document

  21. Towards a Flexible Implant with Distributed Electronics, Wireless Communication and Energy Transfer
    Martins da Ponte, Ronaldo; Vasiliki Giagka; Wouter Serdijn;
    In Book of Abstracts, 6th Dutch Bio-Medical Engineering Conference, 26 and 27 January 2017, Egmond aan Zee, The Netherlands,
    2017.
    document

  22. MEMS-electronics integration: a smart temperature sensor for an organ-on-a-chip platform
    Martins da Ponte, Ronaldo; V. Giagka; W.A. Serdijn;
    In Proc. Design of Medical Devices Conf. (DMD) 2017 Microfabrication for Medical Devices,
    Eindhoven, 14 – 15 Nov 2017.
    document

  23. Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo
    Danial Chitnis; Dimitrios Airantzis; David Highton; Rhys Williams; Phong Phan; Vasiliki Giagka; Samuel Powell; Robert J Cooper; Ilias Tachtsidis; Martin Smith; Clare E Elwell; Jeremy C Hebden; Nicholas Everdell;
    Review of Scientific Instruments,
    Volume 87, Issue 6, pp. 065112, June 1 2016. Publisher: AIP Publishing.
    document

  24. Flexible active electrode arrays with ASICs that fit inside the rat's spinal canal
    Vasiliki Giagka; Andreas Demosthenous; Nick Donaldson;
    Biomedical Microdevices,
    Volume 17, Issue 6, pp. 106 - 118, December 2015. DOI 10.1007/s10544-015-0011-5.
    document

  25. An Implantable Versatile Electrode-Driving ASIC for Chronic Epidural Stimulation in Rats
    Vasiliki Giagka; Clemens Eder; Nick Donaldson; Andreas Demosthenous;
    IEEE Transactions on Biomedical Circuits and Systems,
    Volume 9, Issue 3, pp. 387 - 400, June 2015. DOI 10.1109/TBCAS.2014.2330859.
    document

  26. Flexible Active Electrode Arrays For Epidural Spinal Cord Stimulation
    Vasiliki Giagka;
    PhD thesis, University College London, Analogue and Biomedical Electronics Group, Department of Electronic and Electrical Engineering, January, 28 2015.
    document

  27. Evaluation and optimization of the mechanical strength of bonds between metal foil and aluminium pads on thin ASICs using gold ball studs as micro-rivets
    Vasiliki Giagka; Anne Vanhoestenberghe; Nick Donaldson; Andreas Demosthenous;
    In Proc. Electronics System-Integration Technology Conference,
    Helsinki, Finland, IEEE, pp. 1 - 5, September 2014.
    document

  28. Controlled silicon IC thinning on individual die level for active implant integration using a purely mechanical process
    Vasiliki Giagka; Nooshin Saeidi; Andreas Demosthenous; Nick Donaldson;
    In Proc. 64th Electronic Components and Technology Conference,
    Orlando, Florida, USA, IEEE, pp. 2213 - 2219, May 2014.
    document

  29. A dedicated electrode driving ASIC for epidural spinal cord stimulation in rats
    Vasiliki Giagka; Clemens Eder; Virgilio Valente; Anne Vanhoestenberghe; Nick Donaldson; Andreas Demosthenous;
    In Proc. 20th International Conference on Electronics, Circuits and Systems,
    Abu Dhabi, UAE, IEEE, pp. 469 - 472, December 2013.
    document

  30. In vivo evaluation and failure analysis of an implantable electrode array for epidural spinal cord stimulation in paralysed rats
    Vasiliki Giagka; Anne Vanhoestenberghe; Nick Donaldson; Andreas Demosthenous;
    In imaps-uk Annual Conference MicroTech 2013 Showcasing Microassembly,
    Cambridge, UK, pp. 1, March 2013.

  31. An Implantable Stimulator System For Neuro-Rehabilitation In Paralyzed Rats
    Vasiliki Giagka; Nick Donaldson; Andreas Demosthenous;
    In Young Researchers Futures Meeting - Neural Engineering,
    Warwick, UK, pp. 1, September 2012.

  32. Towards a low-power active epidural spinal cord array controlled through a two wire interface
    Vasiliki Giagka; Andreas Demosthenous; Nick Donaldson;
    In Proc. 8th Conf. Ph.D. Research in Microelectronics and Electronics,
    Aachen, Germany, VDE, pp. 247 - 250, June 2012.
    document

  33. Flexible platinum electrode arrays for epidural spinal cord stimulation in paralyzed rats: An in vivo and in vitro evaluation
    Vasiliki Giagka; Anne Vanhoestenberghe; Nikolaus Wenger; Pavel Musienko; Nick Donaldson; Andreas Demosthenous;
    In Proc. 3rd Annual Conf. International Functional Electrical Stimulation Society UK and Ireland Chapter,
    Birmingham, UK, pp. 52 - 53, April 2012.
    document

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Last updated: 10 Jul 2019