AFFIP -- Atrial Fibrillation FIngerPrinting: Spotting Bio-Electrical Markers to Early Recognize Atrial Fibrillation by the Use o (AFFIP_)

Themes: Analog and Mixed-Mode Integrated Circuits and Systems, Biosignal acquisition, conditioning and processing

STW and DHF project (14728). Program leader: Dr. N.M.S. de Groot (ErasmusMC), workpackage leader WP4, High Density Mapping Array: W.A. Serdijn
Atrial fibrillation (AF) is a progressive disease and associated with severe complications such as stroke. Early treatment of AF is of paramount importance as it inhibits disease progression from the treatable (recurrent intermittent) to the untreatable (permanent) stage of AF.
However, early treatment is seriously hampered by lack of accurate diagnostic instruments to recognize patients who will develop new onset AF or progress to a severer form of the disease.
The goal of this project is to develop age and gender based, bio-electrical diagnostic tests, the invasive and non-invasive AF Fingerprint, which consists of electrical atrial signal profiles and levels of atrial specific tissue/blood biomarkers.
In daily clinical practice, this novel diagnostic instrument can be used for early recognition or progression of AF by determination of stage of the electropathology. As such, AF Fingerprinting enables optimal AF treatment, thereby improving patient's outcome.

Project data

Researchers: Wouter Serdijn; Samprajani Rout
Starting date: June 2016
Closing date: November 2020
Funding: 1102 kE; related to group 551 kE
Sponsor: STW/Hartstichting
Partners: ErasmusMC, VUMC, TU Delft (CAS and BE)
Users: Applied Biomedical Systems, Biosense Webster, Hart&Vaatgroep
Contact: Wouter Serdijn

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