EE4555 Active implantable biomedical microsystems

Active Implantable Biomedical Microsystems (AIBM) in the human body are now becoming more widely acceptable and available since the development of cardiac pacemakers. Today, miniaturized wireless implantable systems are changing the face of biomedical research and clinical practices through the development of cochlear implants, neuroprostheses, brain–computer interfaces, deep organ pressure sensors, precise drug delivery units, bioelectronic medicine and electroceuticals. With a greater life expectancy and an increasing demand for medical healthcare to guarantee a sufficient health-related quality of life, there is a greater demand on technology and electrical and biomedical engineers to develop active implantable systems for a wide variety of medical diagnostics, treatments and therapies.

This course provides a background on the application of AIBMs, an introduction to the latest techniques used and examples of existing medical devices. It can be used as a guide to the design of AIBMs and also as a reference for existing medical devices. The course is aimed at MSc students in Electrical Engineering (track Microelectronics) and in Biomedical Engineering (specialization Biomedical Electronics) who have an interest in the research and design of AIBMs.

The following topics are treated:

1. Electrophysiology
2. Electrodes, optodes, sensors and actuators
3. Electrode characterization and modeling
4. Electronic system design
5. Stimulation electronics
6. Front-end electronics (signal conditioning, amplifiers, filters, ADCs, etc.)
7. DACs and wireless data transfer
8. Energy harvesting and power delivery
9. Applications: cochlear implants and cardiac pacemakers
10. Digital design
11. Biocompatibility, materials and fabrication considerations
12. Assembly, system integration and packaging
13. Application: spinal cord stimulator
14. Reliability and security
15. Clinical and regulatory considerations

Teachers

prof.dr.ir. Wouter Serdijn

Circuits and systems for wearable, implantable and injectable medical devices, in particular electroceuticals and bioelectronic medicine.

dr. Vasiliki Giagka

Design and fabrication of active implantable devices; Analog and mixed-signal integrated circuits for biomedical applications

dr. Tiago Costa

Analog and mixed-signal CMOS circuit design for biomedical applications, including electroceuticals, implantable devices and lab-on-a-chip; microfabrication methods for monolithic integration of transducers in CMOS for biomedical applications.

dr. Dante Muratore

Analog and mixed-signal CMOS circuit design for biomedical applications and sensor interfaces; circuit-algorithm co-design; neurophysiology.

dr.ir. Christos Strydis

High-performance computational-neuroscience applications, dependable computer architectures, low-power embedded systems and biomedical microelectronic implants

Last modified: 2020-10-14