MSc thesis project proposals

Here is a list of possible MSc thesis projects. This is intended just to give an idea, actual projects are usually defined after discussion with the advisor.

[2021] Data Acquisition System for High-throughput Electrophysiological Signals Recording with Microelectrode Array Chip

Biosignal acquisition, conditioning and processing

[2020] Compact Neural Amplifier for Next-Generation Brain-Machine Interfaces. [Already taken]

MSc thesis project for an EE student on the design of a neural amplifier IC for pixel-matched massively parallel neural interfaces.

[2020] Background Calibration and Adaptive Tuning Methods for Time-Mode Subtraction Based Time-to-Digital Converters

In this project, we aim to develop background calibration and biosignal specific (EEG, ECG, ECOG, etc.) adaptive tuning methods for a recently developed asynchronous TDC which utilizes a time-based subtraction method.

[2020] BabyPleister: Health condition monitoring of newborns at home. [Already taken]

The goal of this project is to improve maternity care at home with a sensor patch.

Microsystem integration

[2021] In-ear Heart Rate detection in a custom-fit headset. [with DOPPLE] [Already taken]

An efficient heartbeat sensor for in-ear headsets is very useful for in fitness and health applications.

Neuroprosthetics, - stimulation and -modulation

[2020] Single-Cell Artifact-Free Stimulation for Next-Generation Brain-Machine Interfaces [Already taken]

MSc thesis project for an EE student targeting the design of an artifact-free neural stimulator IC for single-cell resolution neural interfaces.

[2021] Activating neuronal networks using ultrasound. [Already taken]

The goal of this project is to develop a micro-platform to investigate the effects of ultrasound on neuronal differentiation.

[2021] Ultrasonic Scalp – towards high-precision transcranial ultrasound brain stimulation

[2020] To Walk Again: Tackling Technical Challenges for Neuromodulation in Patients with Spinal Cord Injury

2 MSc thesis projects on spinal cord stimulation electronics and electrodes design in collaboration with the departments of Neuroscience, Neurosurgery and the Center of Pain Medicine of Erasmus MC.

[2021] Piezoelectric micro-actuators for high resolution ultrasound brain stimulation

MSc thesis project on modeling, designing, fabricating and testing piezoelectric micro-actuators for high-resolution brain stimulation using ultrasound

[2021] Focused ultrasound vagus nerve stimulation

Design a framework for optimizing the vagus nerve stimulation (VNS) using focused ultrasound (FUS).

[2020] Novel electrical stimulator architectures for long-term implants

In this master thesis project, the student will design novel architectures for electrical stimulation of the tissue, that will be suitable for soft encapsulated implants.

Transcutaneous Wireless Communication

[2021] Body Coupled Communication for Microscale Implants

This project aims to investigate the applicability of body-coupled communication (BCC) for a network of micro-scale implants. The project's main goal is proposing and implementing a lightweight network protocol suitable for implantable micro-scale devices and/or implementation of an energy-efficient tissue interface for the BCC method.

[2020] Body-coupled communication to enhance IMD security

MSc thesis project in collaboration with the implant security experts of ErasmusMC (Dept. Neuroscience) on their holy mission to make active medical implants safe, secure and dependable.

[2021] Network of individually addressable ultrasonically powered implants

MSc thesis project in microelectronics on designing (on chip) light-weight and chip-scale communication protocols and addressing strategies for a network of ultrasonically powered implants

Analog and Mixed-Mode Integrated Circuits and Systems

[2021] Readout Electronics for Time-of-Flight Cameras in Mobile Face-Unlock Applications (project with Infineon) [already taken]

In this project, you will study a novel analog-to-digital converter for next-generation low-power time-of-flight sensor arrays being developed at Infineon. The design will be implemented in 65-nm CMOS technology and verified at the transistor level.

Transcutaneous Wireless Communication

[2020] Event-Based Communication Protocol for Ultra-Low Power Compressive Neural Interfaces

MSc thesis project for an EE student on the design of a protocol for event-based data communication in implantable devices using Verilog.

Wireless Power Transfer, Power Management and Energy Harvesting

[2021] Fully integrated DC-DC Converter for energy harvesting

MSc thesis project opportunity in collaboration with NOWI Energy

[2021] Single-Channel Energy Harvesting Power Converter for Heterogenous Sources

MSc thesis project opportunity in collaboration with NOWI Energy

[2021] Energy Harvesting and Power Management in the Same DC-DC Converter Area

MSc thesis project opportunity in collaboration with NOWI Energy

[2021] High-Efficiency Fully-Integrated Voltage Regulator

MSc thesis project opportunity in collaboration with NOWI Energy

Electroceuticals

[2020] Smart transparent electrode array for electroceuticals

In this project, we wish to take electroceuticals to the next level, by fabricating new, compact, flexible and transparent active neural interfaces.

Flexible implants

[2020] Ultra-Flexible Active-Matrix Electrophysiology Arrays for Neural Interfacing

MSc thesis opportunity for an EE or BME student at the Holst Centre in Eindhoven on the development and characterization of active-matrix TFT arrays on foil with three-dimensional conformability for improved neural interfacing.

[2020] Influence of system integration and soft encapsulation on a wirelessly powered neural interface

Sensors and Actuators

[2021] Electronic anal sphincter device as a surgical treatment option for incontinence

Fecal incontinence is the inability to control bowel movements causing stool to leak out. Fecal incontinence is very common but because of the associated embarrassment and taboo nature, it is under-reported and its true prevalence difficult to reliably assess. If treatment is sought, there is no universal treatment and patients can be left with poor sphincter control or a lack of independence

Microsensors

Hernia post-operative monitoring

Incisional hernia (IH) is a complication which can occur after surgery to the abdomen. In order to prevent IH, a mesh can be used. This holds the tissue in place to reinforce it and to enable healing. However, in some cases the healing does not take place correctly and IH is not prevented. In order to monitor healing, scans or ultrasonography can be used, but these diagnostic tools are expensive and time consuming. The aim of this project is to create a “bionic” mesh which can detect the early stages of IH formation with a device attached to the tissue around the wound.

Microsystem integration

[2020] Active neural interfaces for Bioelectronic Medicine (MSc project at Fraunhofer)

Project outside the university in collaboration with Fraunhofer Institute for Reliability and Microintegration in Berlin, Germany

[2020] A system for blood analysis of newborns using Microneedles (with Stellenbosch South Africa)

This project aims to develop a novel, minimally invasive, detection method for jaundice (geelzucht).

Microsensors

[2020] Ammonia & humidity sensors

Development of a ammonia/humidity sensor for harsh environments.

[2020] Heartbeat measurement by infrared detection in the ear

Non-contact (infrared) temperature measurement in the ear canal is an attractive yet challenging method for heartbeat detection.

Microsystem integration

Self-test for IR Sensors

In many applications, the lens and packaging of IR sensors can become contaminated leading to measurement error and apparent failure. A self-test built into the package could solve this problem. This project concerns the development of a self-test system which can compensate for minor contamination and produce a warning for higher contamination levels.

Medical applications for custom-fit wireless headsets

New wireless headsets, that combine audio applications (music/voice calls) with sensor applications are entering the market. Integration with new sensors in custom-fit headsets provides new opportunities in medical, fitness and home care applications.

Sensors and Actuators

Detection of prostate cancer in urine

Prostate cancer is a major problem for men over the age of 55. Early diagnostic is extremely important. Present techniques are expensive and/or cause great discomfort. This project, in collaboration with The Hague University of Applied Science and Erasmus Medical Centre, aims to address these issues.

Achilles tendon injury and recovery

When the Achilles tendon is overloaded, it is painful and needs to recover. This process is not well understood. This project is directed towards a better understanding of the role of dynamic loading in overloading and recovery of tendon.

Embryo development

This project involves a study of the development of an embryo and the effect of mechanical stress.

Lab-on-a-chip

[2020] Electronic lateral flow immunoassay

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[2020] Unobtrusive monitoring of internal bleeding

Internal bleeding is a major cause of death. This project aims to develop an unobtrusive method for monitoring internal bleeding.

Biocomputing

[2020] Subthreshold Stochastic Computing for On-Chip Low Energy BioSignal Processing

[2020] Subthreshold Bit-Serial Microprocessor Design for On-Chip Low Energy BioSignal Processing

Sensors and Actuators

Modelling for fontain circulation in congential heart disease

Children born with a single-ventricle heart defect need a series of operations, otherwise they will die in the first week of their life. Since the dysfunctional ventricle cannot be repaired, surgeons connect the functional ventricle to the aorta and the venous blood flow is redirected such that it passively returns to the lungs, thereby bypassing the heart. The final result is a so called Fontan circulation (Figure left panel). Patients with a Fontan circulation often suffer from limited exercise capacity, which is thought to be related to the geometry of and the altered hemodynamics in the Fontan circulation. Moreover, these patients use medication their entire life to avoid blood clotting.

[2020] Active Acoustic Channel for Dynamic Hearing Protection

Bioelectronics

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